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At Bariatric Guru in Los Angeles, we specialize in advanced surgical solutions for severe obesity, including one of the most powerful and innovative procedures available today: Single-Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy (SADI-S). This procedure combines the best features of two established weight loss surgeries—the sleeve gastrectomy and the duodenal switch—to deliver long-term, transformative results.

What Is SADI-S?

SADI-S is a hybrid bariatric procedure that begins with a sleeve gastrectomy, where approximately 70–80% of the stomach is removed, reducing hunger hormones and limiting food intake. Next, the small intestine is rerouted with only one connection (anastomosis) between the duodenum and the ileum, offering a simpler version of the traditional duodenal switch.

This “best of both worlds” approach allows patients to benefit from both restriction (smaller stomach) and malabsorption (fewer calories and nutrients absorbed), which significantly enhances weight loss while minimizing complications associated with more complex surgeries. Benefits of SADI-S include:

  • Rapid and Sustained Weight Loss: Most patients lose 75–85% of their excess weight within 12–18 months after surgery.
  • Improved Metabolic Health: SADI-S is especially effective for improving Type 2 diabetes, hypertension, sleep apnea, and high cholesterol.
  • Lower Risk of Nutritional Deficiencies: Compared to traditional duodenal switch, the simplified structure of SADI-S offers better control of nutrient absorption.
  • Fewer Complications: With only one anastomosis, the risk of intestinal leaks or strictures is reduced.
  • Appetite Control: Ghrelin production is significantly decreased, resulting in lower hunger levels and better control over food intake.

Who Is a Good Candidate?

SADI-S is most suitable for individuals with:

  • A BMI of 40 or higher (or BMI over 35 with serious comorbidities)
  • A history of failed weight loss through diet, exercise, or medication
  • Metabolic conditions like diabetes or insulin resistance
  • A desire for a long-term solution with fewer side effects than traditional bypass

SADI-S is also an excellent option for patients who have had previous bariatric surgeries, like sleeve gastrectomy, and are seeking revision due to weight regain.

Los Angeles’ Trusted SADI-S Experts

At Bariatric Guru, we serve patients throughout Los Angeles County, including Beverly Hills, Santa Monica, Glendale, and Long Beach. Dr. Lalezari is highly experienced in minimally invasive SADI procedures and works closely with patients from consultation through post-op care to ensure optimal results.

According to recent studies, SADI-S shows comparable weight loss outcomes to the classic duodenal switch with fewer complications and improved long-term sustainability.

Ready to Take the Next Step?

If you’re struggling with severe obesity and haven’t found success through other methods, SADI-S may be the life-changing solution you’ve been looking for. This advanced procedure offers dramatic results with less complexity, and our Los Angeles team is here to support you every step of the way.

Contact Bariatric Guru today to schedule your consultation and find out if SADI-S is right for you.

Posted on behalf of Bariatric Guru


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Our Patient Story

BARIATRIC SURGERY

“…I never thought of losing more than 30lbs. Its not only a physical change, it is my self-esteem, my health and emotionally I am a new person. Thank you Dr. Lalezari for supporting me, motivating me and being aware of my process and my health day by day. Last week I reached my goal of 140lbs. Thank you!!!! You’re the Best”

Claudie
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Start Your Weight Loss Journey Today

Take the first step towards a healthier, happier you. Contact Bariatric Guru in Los Angeles to schedule a consultation and discover the right weight loss solution for you. Whether you are considering bariatric surgery, non-surgical treatments, or looking to enhance your beauty and wellness, Bariatric Guru is here to guide you every step of the way.